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NeurotransmitterTypeDerived FromClinical Relevance
GABAAmino acidGlutamateThe most ubiquitous. Involved in sleep, anxiety reduction, muscle relaxation. Involved in relaxing effects of alcohol.
L-tryptophan (L-T)Amino acidCan only be obtained in the diet.Promotes sleep, especially when taken with a high carbohydate, low protien meal. Dangerous when consumed with MAO antidepressants.
Tyramine (Tyr)Amino acidFats and carbohydatesDangerous when consumed with MAO antidepressants.
Glutamate (Glu)Amino acidFats and carbohydatesMSG reaction to Chinese food. The major excitatory amino acid. May be associated with neurotoxic effect in alcoholism.
Dopamine (DA)Biogenic amineTyrosine, fats, and carbohydatesMania, schizophrenia, Parkinson’s diease, attention deficit disorder, substance abuse, tics, blood pressure regulation. Antipsychotics (major tranquilizers) inhibit DA action. Some antidepessants act here.
Norepinephrine (NE)Biogenic amineDopamineDepression, anxiety, panic, blood pressure regulation. Necessary for learning and memory.
Serotonin (5-HT)Biogenic amineL-tryptophanDepression, mania, anxiety, blood pressure and temerature regulation. Many antidepressants, new antipsychotics, and nonadicting antianxiety agents act on these conditions via this neurotransmitter.